My lab works with a range of different drugs. We often treat cells with chemotherapy agents commonly used in the clinic to observe the effects they have on the cells. Other times we get new drugs from companies who want us to test them out and see what happens to the cells when they are treated with the new drugs. Quite often we will try and get drugs that target specific pathways that we are interested in. Signalling pathways in cells often determine how they behave, so having drugs that target pathways which think might be important is a very useful tool. In my experiments I often use both common and new drugs to treat my cells and observe the changes in them.
Hi Karadolphins, I am not working with any known commercial drugs. Instead, one of the long-term goal of my research is to develop novel therapeutics which will prevent cardiovascular diseases.
I don’t currently use any drugs in my work. What I’m doing comes well before we get to the stage of drug testing. I hope that what we understand about cancer from my research, will allow others to search for new drug targets based on what I discover.
I have used many chemotherapy drugs before, much like Cindy. I also now use pencillin, streptomycin, kanamycin, ampicillin, gentomycin, chloramphenicol and erythromycin. Some of those you might have been prescribed when you have a bacterial infection as they are antibiotics, and we use them to work out which bacteria are resistant to them, which pumps can spit them out of the bacteria, and also we include the resistance gene for one of these usually when we put the DNA from the superbugs into more harmless E.coli to grow the protein. If we grow the cells in the presence of the antibiotic and they grow, we know they are only the ones with the DNA we put in it, and the ones which will make out protein
Thanks for your question karadolphins.
My lab works with a range of different drugs. We often treat cells with chemotherapy agents commonly used in the clinic to observe the effects they have on the cells. Other times we get new drugs from companies who want us to test them out and see what happens to the cells when they are treated with the new drugs. Quite often we will try and get drugs that target specific pathways that we are interested in. Signalling pathways in cells often determine how they behave, so having drugs that target pathways which think might be important is a very useful tool. In my experiments I often use both common and new drugs to treat my cells and observe the changes in them.
1
Hi Karadolphins, I am not working with any known commercial drugs. Instead, one of the long-term goal of my research is to develop novel therapeutics which will prevent cardiovascular diseases.
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I don’t currently use any drugs in my work. What I’m doing comes well before we get to the stage of drug testing. I hope that what we understand about cancer from my research, will allow others to search for new drug targets based on what I discover.
1
I have used many chemotherapy drugs before, much like Cindy. I also now use pencillin, streptomycin, kanamycin, ampicillin, gentomycin, chloramphenicol and erythromycin. Some of those you might have been prescribed when you have a bacterial infection as they are antibiotics, and we use them to work out which bacteria are resistant to them, which pumps can spit them out of the bacteria, and also we include the resistance gene for one of these usually when we put the DNA from the superbugs into more harmless E.coli to grow the protein. If we grow the cells in the presence of the antibiotic and they grow, we know they are only the ones with the DNA we put in it, and the ones which will make out protein
1